• Recognize

    Serum chemistry/hematology abnormalities Infectious vs immune-related adverse event causation Peritoneal signs of bowel perforation (i.e., pain, tenderness, bloating)

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  • Listen

    Quantity & quality of bowel movements (e.g., change in/increased frequency over baseline): solid, soft, or liquid diarrhea; dark or bloody stools; or stools that float Fever Abdominal pain or cramping Increased fatigue Upset stomach, nausea, or vomiting Bloating/increased gas Decreased appetite or food aversions

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  • Look

    Does the patient appear weak? Has the patient lost weight? Does the patient appear dehydrated? Does the patient appear in distress?

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