Symptom: Yellowing of Skin or Eyes

Initial Grading Reminder


Assessment and Grading

Characterize the symptom (onset, pace)

Ask the patient:

Have you ever had issues with your liver in the past? Is this yellowing a new or worsening symptom? When did it start or get worse? Has it developed gradually or suddenly? Where did you notice the yellowing? In your eyes, skin, or tongue?

Grade the symptom


Patient Query Regarding Other Symptoms/Red Flags

Ask the patient:

Do you have severe abdominal (belly) pain or sleepiness? Are you feeling foggy?

Patient Factors to Consider That Affect the Approach to Intervention

Consider the following in individualizing the intervention: Is the patient a good or poor historian? Any language barriers or cognitive deficits? Is the patient reliable (able to carry out treatment recommendations)? Does this patient have alcohol/substance abuse issues? Does the patient have transportation? Is there sufficient caregiver support?

  • Click Here for Telephone Triage

    Suggested Intervention

    Patients with any yellowing should be seen.

    Patients with the red-flag symptoms should be seen immediately.

  • Click Here for In-Office Triage

    Nursing Assessment of Potential Causes

    [tab category='Hepatotoxicity' header="Hepatotoxicity - Nursing Assessment" tab1='Look' tab2='Listen' tab3='Recognize']

    Differential Diagnosis

    What do you suspect is the cause of yellowing of the skin or eyes?