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		May 8, 2018 at 12:16 am
		
		#4832
		
		
		
	
Hi Lisa–
such a great question. I agree with Rajni. The oral targeted therapies are very challenging for many patients. There will definitely be a select group of patients in which these agents are used in the adjuvant setting, but the pyrexia and febrile syndrome make them quite challenging in more advanced melanoma patients.