The Melanoma Hub – Home Forums Immunotherapy Side-effect management Standard Doses – pembrolizumab Reply To: Standard Doses – pembrolizumab


There are no standard dosage reductions for irAEs associated with pembrolizumab. The dose is either held until the irAE resolves sufficiently (typically to Grade 0 or Grade 1) or, if the irAE is severe enough, pembrolizumab is discontinued permanently.