CTCAE grading of sweating, increased:
Grade 1: Limited to one site (palms, soles, or axillae); self-care interventions
Grade 2: Involving >1 site; patient seeks medical intervention; associated with psychosocial impact
Grade 3: Generalized involving sites other than palms, soles, or axillae; associated with electrolyte/hemodynamic Imbalance
Characterize the symptom (onset, pace)
Ask the patient:
Have you had any issues with increased sweating in the past? (if relevant: Are you perimenopausal?) Is this a new or worsening symptom? When did it start or get worse? Has it developed gradually or suddenly? Are you sweating all the time or at specific times?
Grade the symptom
Ask the patient:
How much are you sweating? Where are you sweating? Is it affecting your ability to function? Are you feeling weak?
Ask the patient:
Do you have any abdominal (belly) pain? Any nausea or vomiting? Do you have a fever and/or chills? Do you feel like your heart is racing? Do you feel hot?
Consider the following in individualizing the intervention: Is the patient a good or poor historian? Any language barriers or cognitive deficits? Is the patient reliable (able to carry out treatment recommendations)? Does this patient have alcohol/substance abuse issues? Does the patient have transportation? Is there sufficient caregiver support?
Patients with new-onset moderate or worse (or worsening) sweating should be seen.
Patients with any of the red-flag symptoms should be seen immediately.
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What do you suspect is the cause of increased sweating?