Note: Palpation of the gland with appropriate thyroid nodule workup is indicated. Grading criteria below are for neck swelling related to rapid thyroid enlargement and effects of compression (i.e., red-flag symptoms).
CTCAE Grading of Swollen Neck:
Grade 1: Asymptomatic localized neck edema
Grade 2: Moderate neck edema; slight obliteration of anatomic landmarks; limiting instrumental ADL
Grade 3: Generalized neck edema (e.g., difficulty in turning neck); limiting self-care ADL
Assess for pre-existing causes of lumps in the neck, including thyroid nodules and cervical nodal metastases.
Characterize the symptom (onset, pace)
Ask the patient:
When did the you notice the lump? How big is it? Has it developed gradually or suddenly? Is your neck swollen? Have you had any swelling of your neck/thyroid gland in the past?
Ask the patient:
Is your neck swollen? Any changes in your voice? Do you have difficulty turning your neck? Any difficulty breathing?
Consider the following in individualizing the intervention: Is the patient a good or poor historian? Any language barriers or cognitive deficits? Is the patient reliable (able to carry out treatment recommendations)? Does this patient have alcohol/substance abuse issues? Does the patient have transportation? Is there sufficient caregiver support?
Patients with thyroid nodules should be seen.
Patients with any of the red-flag symptoms should be seen immediately.
What do you suspect is the cause of the neck lump?